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The device and the tobacco sticks (HEETS Bronze) used are commercially available

Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]

Pediatr Nephrol 14:3638

As the disease is incurable and death inevitable 35 years after the diagnosis, more extensive investigations are required in order to discover potential novel early biomarkers and therapeutics

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