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It is crucial for mood, motivation, and motor control

Inflammatory factor expression Fasting venous serum samples were collected on preoperative day 1 and postoperative day (POD) 3 to detect tumor necrosis factor alpha (TNF-), interleukin (IL)-6, and prostaglandin E 2 (PGE2) expression levels using enzyme immunoassays (R&D Systems, Inc., Minneapolis, Minnesota, USA)

Individuals with one or two copies of the genetic variation and low activity of the MTHFR enzyme may present with elevated homocysteine levels, which have been associated with inflammation, heart disease, pregnancy complications, and even miscarriages