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4.6
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Description

The Mediterranean and Middle East face challenges with Leishmania infantum and Leishmania tropica , where antimonial resistance is emerging, leading to increased reliance on L-AmB

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Legal status (US): Not FDA-approved for any human indication

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It occurs obligatorily due to the abundance of carbohydrates as metabolic intermediates

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Gastroenterology 148 , 379391.e374 (2015)

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Vitamin D metabolism is dysregulated in asthma and chronic obstructive pulmonary disease

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Secalonic acid A reduced colchicine cytotoxicity through suppression of JNK, p38 MAPKs and calcium influx

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