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COX, R., GOORHA, S., & IRVING, C.C

A Glutation testnk egyik legersebb antioxidnsa, ami rendkvl hatkonyan kpes eltvoltani a szabadgykket a szervezetbl, s kzd azok krost hatsai ellen

2021 Oct 1;115:8-22

NAC acts as a powerful antioxidant that helps neutralize oxidative stress before it damages skin cells

Depletion of GPx special in severe patients leads to the accumulation of H 2 O 2 , which may subsequently reacts forming hydroxyl radical (OH) through the Fenton reaction leading lipid peroxidation, DNA damage and cell death [7, 24]

Mechanistically, this strategy led to the downregulation of NF-B, activation of FADD, and increased expression of APAF1 and E-cadherin, while suppressing tumour-promoting factors such as Survivin, MDR1, STAT3, Akt, PI3K, and vimentin [253]