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Do not exceed 5 days of systemic therapy

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thus requiring elucidation of better alternatives with robust antioxidant capabilities to promote neuronal health in PD

The tissue was disrupted using tissue homogenizer Bio-Gen PRO200 homogenizer (PRO Scientific, Oxford, CT, USA), in 1000 l of TRIzol (Invitrogen, Thermo Fisher Scientific, Waltham, MA, USA) and the isolation itself was done using a TRIzol-based reagent method according to the manufacturers instructions