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These cascades function cooperatively to promote hepatocyte survival and replication during regeneration

This would be especially true for drugs relying on a fine functional remodulation of a well preserved cellular system, like the NRF2 activators on the KEAP1-NRF2 system

Free radicals, antioxidants, and nutrition

By serving as a highly efficient delivery system for L-cysteine, NAC rapidly replenishes the intracellular stores of glutathione

NADPH, a major cellular reductant, supports the enzymatic activity of FSP1, which resides on the plasma and outer mitochondrial membranes