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Cancers 13 , 40 (2020)

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In comparison to prior narrative syntheses that propose putative mechanisms without systematically evaluating lipid pathways, the present review advances the field by integrating findings from experimental, preclinical, and translational studies to map how UPF consumption alters lipid synthesis, transport, and signaling within the central nervous system

781 Over the years, various modification strategies have emerged, including those based on 2-O-methyl, 2-O-methoxyethyl, 2-fluoro, and n-acetylgalactosaminyl, aiming to preserve the therapeutic attributes of nucleic acids while enhancing their stability

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