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The CDK6 protein is often involved in controlling the G1/S transition of the cell cycle and is overexpressed and hyperactivated in several types of cancer, ultimately promoting uncontrolled cell growth of cancer cells

doi: 10.1097/00006842-200111000-00016 59 Fernandez-RealJ-MPugeatMGrasaMBrochMVendrellJBrunJet al

BNIP3 mediates pre-myelinating oligodendrocyte cell death in hypoxia and ischemia

In autophagy-deficient cells, intracellular iron and lipid peroxidation were decreased, resulting in cells that could become resistant to erastin-induced ferroptosis [70]

J Exp Biol 213:33323339

Aggregated -synuclein will obstruct synaptic transmission, mitochondrial function, and protein degradation pathways, contributing to dopaminergic neuron loss