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Danggui Buxue decoction can reduce the content of ceramides (Cers), phosphatidylethanolamine, and phosphatidylcholine in the kidneys of mice by downregulating the transcription levels of Degs2 and Cers, reducing lipid accumulation, promoting Akt phosphorylation, and alleviating lipid accumulation as well as renal injury [156]

doi: 10.1111/j.1365-2133.1995.tb02752.x 39

Noncoding RNAs and their regulated signaling pathways Noncoding RNAs are key epigenetic regulators of gene expression that account for the regulation of cell homeostasis and control a wide range of diseases

The most prevalent ROS reported to affect lipids profoundly include HO and hydroperoxyl (HO 2 )

Higher levels of pro-inflammatory bacteria like Flavonifractor and lower levels of Christensenellaceae have been associated with oxidative stress, low-grade inflammation, and more severe symptoms in individuals with BD