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As discussed in our previous review (Reference Ashoori and Saedisomeolia12) , in some cases, riboflavin has led to a decrease in oxidative stress, while the activity of antioxidant enzymes has not increased concurrently, a finding that has been reported in recent studies as well (Reference Btn, Nazrolu and Demirci24)

10.1371/journal.pone.0223302 [DOI] [PMC free article] [PubMed] [Google Scholar] 85.El-Eshmawy MM et al

It is commonly overexpressed in numerous human malignancies as a newly identified survival strategy by providing an additional safeguard through the enhancement of GLO1 detoxification ( Of the remaining two genes, members of the LC8 family of dynein light chain isoforms (DYNLL1 and DYNLL2) are ubiquitous, highly conserved eukaryotic homodimer proteins in addition to dynein and myosin 5a motor proteins, with numerous (still incomplete) proteins involved in diverse cellular processes ( via its FERM, SAB, and CT domains

A study conducted in 2019 indicated that a deficiency in selenium elevates the risk of developing hyperthyroidism in patients with Graves disease and those suffering from nodular goiter

During the course of a pregnancy, the growing fetus has substantial nutritional and energy needs, especially in the later trimesters, and the body also prepares for even greater energy demands in the future (Castillo-Matamoros & Poveda, 2021)

Overall, these observations thus indicate that in iRBD, the disease process extends beyond the sleep-related structures in the brainstem to other structures, including the nigrostriatal system [186, 187]