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In our study, after 24 weeks of treatment, L-glutamine did not cause a reduction in hemolysis markers nor improvement of hemoglobin level, as there was no difference between the two groups except at week 12, the reticulocyte count was higher in those on SOC

Wei et al., 2019)

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The GT activity was increased by 11.13 folds (42.9 mol/mg/min) with 40.4% yield, compared to the crude enzyme upon purification by Sepharose 4B column

E12 embryos: n = 12 Slc25a39 fl/fl or Slc25a39 fl/- , n = 7 ErGFP-cre +/- Slc25a39 fl/- , n = 4 ErGFP-cre +/- Slc25a39 fl/fl

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