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PLGA nanoparticles loaded with either loperamide or doxorubicin were coated with PS80 or P188 and tested in vivo in rodents [56]

Esses achados reforam o interesse cientfico pela molcula, mas no validam uso esttico injetvel em humanos

GPX4 consumes GSH to reduce lipid hydroperoxides (L-OOH) to lipid alcohols

J., Schmeissner, U., Hofer, M

BHBA and acetoacetate reduce glutamate-induced free radical formation by increasing the nicotinamide adenine dinucleotide (+)/ nicotinamide adenine dinucleotide hydrogen ratio and strengthening mitochondrial respiration (133), and prevent mitochondrial permeability transition and oxidative injury (134, 135)

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