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3.9 In Vivo characterization 3.9.1 Behavioural parameter Behavioural parameters like rotarod, actophotometer, and balance beam are assessed in Parkinsons disease to evaluate motor coordination, activity levels, and balance, which are commonly impaired in the condition and the scores of each parameter is depicted in Figure 5 ( FIGURE 5 3.9.2 Rotarod analysis On day 0, no significant differences in rotarod performance were observed across the groups, establishing a baseline for motor coordination