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Figure 4 Figure 5 The Ferroptosis Inducer RSL3 Suppresses CRC Regrowth After 5-FU Therapy Cessation In Vivo To confirm the anti-tumor regrowth effect of GPX4 inhibition after the removal of anti-colorectal cancer agents, we used a subcutaneous tumor mouse model

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doi: 10.1016/j.immuni.2018.11.003 80 WeinmllnerRZbiralBBecirovicAStelzerEMNagelreiterFSchossererMet al

Bile acids and their effects on diabetes

Results from these multi-scale approaches reveal that cysteines 8 and 83 are the main targets of glutathionylation and oxidation that lead to loss of activity, while cysteine 79 is less vulnerable to oxidation

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