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Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply

Functioning as a free radical scavenger, it plays a pivotal role in safeguarding our DNA, cellular lipids, and proteins from the detrimental effects of oxidative stress, earning it the esteemed title of "master antioxidant."

For instance, the total NADP(H) is about 420 nmol/g wet weight in rat liver and 59% of total NADP(H) is found in mitochondria, and 30 nmol/g wet weight in skeletal muscle, 5,8 and the NADPH concentration in the cytosol is 3.1 0.3 and 37 2 M in the mitochondrial matrix in HeLa cells

Van Hove I, De Groef L, Boeckx B, Modave E, Hu TT, Beets K, et al

In: Anti-diabetes and anti-obesity medicinal plants and phytochemicals: safety, efficacy, and action mechanisms

DSIP also demonstrates effects on the opioid system in the brain