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10.1007/s11481-009-9176-0 Front

Advanced Drug Delivery Rev (2020) 165-166:114

Zanatta A, Rocha AM, Carvalho FM, Pereira RMA, Taylor HS, Motta ELA, et al

549 Phase I studies showed that a single subcutaneous dose of zilebesiran of 200 mg or more considerably decreased serum AGT levels and 24 h ambulatory blood pressure for up to 24 weeks, with only mild injection site reactions observed