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Across the six published trials, the most common adverse events were headache, mild gastrointestinal effects (diarrhea, flatulence, nausea), nasopharyngitis, fatigue, dizziness, and mild injection-site reactions

2015;10:e0134927

Weight loss with Tesofensine was primarily fat mass, with a notable preservation of lean mass as assessed by DEXA. Astrup et al., The Lancet May Improve Training Drive and Mood Elevated dopamine and norepinephrine levels can enhance motivation , focus , and mental resilience during challenging cutting phases