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The resulting cells were washed twice with PBS and stored at 20 C

found that co-exposure of silica nanoparticles and BaP activate the AP-1/c-Jun and MAPK/PI3K signaling pathway, upregulate the expression of proinflammatory and procoagulant genes

This, in turn, sparks inflammation and promotes the homing of circulating immune cells to the liver, consequently affecting the functionality of hepatic immune cells[21]

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Notably, 1,162 downregulated and 1,233 upregulated genes induced by CCl 4 were reversed by MSC treatment, suggesting these DEGs may play crucial roles in MSCs therapeutic effects (Fig

Furthermore, long-term treatment of animals with Echi-E did not change the frequency of cilia beating, maintaining its basal levels, which allowed mucociliary clearance