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Role of the C9ORF72 gene in the pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia

Continuous liver damage due to the overproduction of ROS and inflammation by diverse endogenous and exogenous injuries, failure at the respiratory chain in mitochondria [10,11], drop-in antioxidant elements such as superoxide dismutase [12], catalase activity [13], or the elevation of lipid peroxidation [14], among other described mechanisms, working together, are involved in injuries, apoptosis, inflammation, and fibrosis [10]

Before sectioning, all the equipment and samples were left inside the cryostat for about 5 minutes for temperature adjustment

Recently, the glymphatic system and dural lymphatic vessels have been proposed as major extracellular disposal routes of A 47