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[DOI] [PMC free article] [PubMed] [Google Scholar] [165].Chen X, Xue H, Fang W, Chen K, Chen S, Yang W, Shen T, Chen X, Zhang P, Ling W, Adropin protects against liver injury in nonalcoholic steatohepatitis via the Nrf2 mediated antioxidant capacity

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Experimental design After 1 week of acclimatization, the rats were randomly and equally allotted into three groups, of 20 animals each, and designated groups 1, 2, and 3

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Results from qRT-PCR and Western blot analyses indicated that TCF12 overexpression effectively counteracted the inhibitory effect of the PD-1 inhibitor on TGF-1 expression (Figures 4J, K) and secretion (Figure 4L) in HCAECs

Furthermore, they showed that the urea cycle plays an active role in reducing intracellular ammonia levels, which supports the long-term survival of memory T cells (104)