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The role of autophagy and mitophagy in cancer Autophagy and mitophagy are deeply intertwined with cancer biology, acting as context-dependent regulators that can either suppress tumor initiation or promote tumor survival and progression depending on tumor stage, metabolic state, and microenvironmental stressors

Furthermore, ACE did not activate caspase-3, suggesting that ACE suppressed mouse tumor growth independent of apoptosis (Fig

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Healthcare providers are encouraged to report any unexpected adverse events through the FDA MedWatch program (www.fda.gov/medwatch or 1-800-FDA-1088) to contribute to the collective understanding of tirzepatide's safety

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