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DDB1 increases poly-ubiquitination and degradation of PHGDH, inhibiting colorectal cancer growth and stemness via an enzyme-independent mechanism

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Ntasi G., Tsarbopoulos A., Mikros E., Gikas E

GH secretagogue was developed for therapy in osteoporosis and muscle wasting, but the official manufacturing of Ibutamoren was discontinued due to a lack of effectiveness in clinical studies