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Looking ahead, continued research into HDAC6's mechanisms of action, the development of highly selective inhibitors, exploration of combination therapies and identification of predictive biomarkers will be crucial for translating preclinical success into clinical practice

This can be modified to be used in autoimmune diseases where a specific pathogenic antibody is identified, by using an engineered T cell which can bind the specific autoreactive B-cell

[DOI] [PubMed] [Google Scholar] 181.Chapman R.G., Schaumburg L

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