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ELEVATED LDL-C AND RISK FOR ASCVD Genetic Causes of Elevated LDL-C As described above, FH is an autosomal dominant inherited disorder associated with elevated levels of LDL-C and premature ASCVD, and provides some of the most compelling evidence for a causal role for LDL-C in atherosclerosis

An in-depth review on the derivatization of ACC is given by Van de Poel and Van Der Straeten (2014)

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Acknowledgments The authors acknowledge Dr