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The half-life of cagrilintide is 159-195 hours (approximately 6.6 to 8.1 days) making it suitable for once weekly subcutaneous administration [5]

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These variations influence the balance between different network activities, leading to altered responses in the salience, visual, internal reward, and executive control networks, thereby highlighting the complex interplay between DA, reward network dysregulation, and the manifestation of depressive symptoms in CID patients (Gong et al., 2023)