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Description

The Raun 1998 paper is an animal study

Brand: Sunshine Nutrition

doi: 10.1002/mnfr.202200884

The protein aggregation and subsequent Fe-S cluster disruption induced by copper overload activate cellular protein quality control pathways, including the increased expression of molecular chaperones such as heat shock protein 70 (HSP70), which attempts to mitigate the proteotoxic burden (8,160)

Ferrandina, G

Despite these improvements, significant diagnostic delays persisted, particularly those patients with predominantly nonmotor or atypical symptoms [50]