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However, GLUT2 and GLUT5 expression was reduced in Caco-2 cells after metformin treatment, with no significant changes observed in the other transporters (Fig

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This study analyses the complicated link between intestinal I/R damage and bloodbrain barrier (BBB) compromise, highlighting essential processes such as systemic inflammation, gut microbiota dysbiosis, oxidative stress, vagus nerve activation, and altered gut microbial metabolite production