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Classical FD (HHC type 4A) is due to loss of function mutations in SLC40A1 that impair iron export

It has been reported that treatment with UK-5099, an inhibitor of mitochondrial pyruvate carrier (MPC), reduces the cellular GSH level by diverting glutamine metabolism from GSH synthesis in tumor cells 37

Every minute it spends at room temperature is a minute it's degrading faster than it needs to

Nucleic Acids Res 39 , e142 (2011)

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