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Drugs that cause AIH-like DILI with positive autoantibodies include minocycline, statins, hydralazine, and nitrofurantoin

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Various kinases are subsequently recruited and promote the transcription of cytokines, including the multifunctional interferons (IFNs) and pro-inflammatory cytokines [16]

The vector also includes a Zeocin resistance gene for selection, and the presence of an AOX1 promoter allows for the methanol-inducible expression of the inserted gene, offering control over the expression levels

Martins LL, Mourato MP