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10.3389/jpps.2023.11808 50 NagappanA.KimJ.-H.JungD

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Similarly, the expression and requirement of cytosolic and mitochondrial isoforms of aspartate and alanine aminotransferases are tissue- and tumour- specific

In this pathology, IGF-I levels diverge between studies, from increased to decreased IGF-I concentrations[330332], probably due to differences in samples origin (serum/cerebrospinal fluid vs spinal cord/musculoskeletal) and could be explained as a physiological defensive mechanism promoted in response to the neural degeneration and/or muscle atrophy