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Deubiquitinated arrestins interact with G and enters the nucleus via importin complex, sequestering G from the receptor and G, which reduces receptor signaling efficiency (desensitization)

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Diabetes (2002) 51:24205

For SureBeads, the beads were pre-incubated with the GFP antibody, washed, and then incubated with lysates for 1 h at 4 C with gentle agitation

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