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Future studies should therefore assess community stability and functional microbial fidelity to strengthen Gut-on-a-Chip platforms as host-integrated culturomics systems for microbiome-dependent drug metabolism

(2021) evaluated the in vitro release of CUR using the dynamic dialysis method, showing that 60% of the polyphenol was released from dimethyl sulfoxide (DMSO) within the first 8 h of administration [20]