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In diabetes, high blood sugar leads to excess production of reactive oxygen species (ROS), which consume glutathione as the body tries to neutralize these harmful molecules, depleting its levels

A3 receptor antagonists lower IOP by preventing adenosine-induced activation of Cl- channels in ciliary epithelial cells, while A2A receptor activation in Schlemm's canal cells can have bidirectional effects on IOP (90, 92)

75 (Suppl 10): C146-51

All the authors of the present study declare no conflicts of interest

Similarly, QT by itself does not change the intestinal GSH content, but it prevents the GSH depletion produced by the quinone[52]

Consistent with it, increasing evidence suggested that copper-induced oxidative stress contributed to cellular inflammatory responses (Yang et al., 2020