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While advances in bioinformatics and nanoformulations are enhancing their pharmacokinetic profiles and clinical applicability, challenges such as standardization, dosage optimization, and translational validation hinder their widespread clinical adoption

388 Anti-inflammatory nanoparticles have been shown to enhance muscle function in a mouse model of advanced muscular dystrophy

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Liver cirrhosis and hepatorenal syndrome Hepatorenal syndrome (HRS) is a serious complication mainly manifested by renal injury in patients with severe liver diseases such as cirrhosis combined with ascites ( in vivo is reduced, which leads to the dilation of visceral and peripheral arteries, the contraction of renal vessels, the reduction of glomerular filtration rate and the decrease of renal blood flow, and finally the occurrence of HRS (Sobhonslidsuk, 2015