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Heat shock protein 27 was up-regulated in cisplatin resistant human ovarian tumor cell line and associated with the cisplatin resistance

In recent years, TCM has achieved advances in medicine with its diverse efficacy, safety, effectiveness and cost-effectiveness, and has been widely used in the prevention and treatment of osteoporosis [14,15,16]

HCN regulates cellular processes through posttranslational modification of proteins by S-cyanylation

As a broad-spectrum antioxidant, NAC may act synergistically with other antioxidant nutrients, potentially enhancing the bodys total antioxidant capacity through complementary mechanisms

doi: 10.1097/MBC.0b013e32832e05f0 124

For this purpose, we intentionally demonstrate the previously reported effects of various antioxidants in the treatment of CIPN, such as melatonin and NAC, with current evidence from preclinical and clinical studies, showing that they can improve mechanical allodynia and related pain perception indicators