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The staining solution was replaced with phenol red free L-15 medium with 10% FBS and 1% penicillin/streptomycin and mitochondria visualized by confocal microscopy (Zeiss LSM710, 63 NA 1.4 oil objective)

Within neurons, oxidative stress may stem from mitochondrial dysfunction induced by the intracellular accumulation of hyperphosphorylated tau and A [84, 120]

sections were washed with distilled water, dehydrated in graded ethanol (70%, 85%, 95%, and 100%), placed in xylen, and cover-slipped using mounting medium

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Kaplan-Meier analysis and Cox proportional hazards modelling indicated that dexamethasone mitigated the risk of fluoroquinolone-induced tendinopathy with a hazard ratio of 0.58 (Figure 3A, 95% CI: 0.340.98, p = 0.04 in the log-rank test)

The FDA had said it would issue proposed rules for over-the-counter acetaminophen by the end of August