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With consistent use, it helps restore softness and luster, making hair more practical and easier to style

J Biol Chem 2005;280:1703845

The underlying mechanism(s) linking reduced IGF-1 signaling to improved mammalian lifespan is thought to involve improved stress defenses and lower risk for proliferative diseases 9,10,11 , though the reason for sex differences in this response remains unresolved

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This work represents one of the first demonstrations of FOXO4-DRI activity in primary human cells, supporting translational relevance beyond the initial mouse model findings

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