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Additionally, a marked correlation between lactylation and inflammation has been observed

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FIGURE 1 The phosphoinositide 3-kinase-Akt-mammalian target of rapamycin (PI3K-Akt-mTOR) signaling pathway, commonly activated in cancer, including AML, contributes to the maintenance of glycolysis by translational and post-translational regulation of metabolic enzymes (Nepstad et al., 2020)

Patients with chronic kidney and cardiovascular diseases have a higher risk of fatality, especially if the water retention symptoms are significantly high or have worsened