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Baron, R., Tolle, T

The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation

used a microfluidics-based aorta smooth muscle-on-a-chip model to show that mitochondrial fusion activators or fission inhibitor can partially rescue the disorders of mitochondrial dynamics in human aorta smooth muscle cells derived from patients with the potential to develop thoracic aortic aneurysms due to a bicuspid aortic valve ( 3.2 Role of models in drug discovery and development The development of effective therapeutics for mitochondrial diseases relies heavily on the insights gained from preclinical models

Hypertension 76 (1), 101112

The short- and long-term outlook for the patient depends on the reversibility of the injury and the recovery

Not reaching HDV TND at EOT had a 97% NPV for sustained HDV TND