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The concern is that unmetabolised folic acid may compete with naturally occurring folate for enzyme binding sites, potentially impairing normal folate-dependent metabolism

Sai Swaroop R, Akhil PS, Sai Sanwid P et al (2022) Integrated multi-omic data analysis and validation with yeast model show oxidative phosphorylation modulates protein aggregation in amyotrophic lateral sclerosis

GrDEVs naturally carry specific plant miRNAs (such as aly-miR396a-5p and rlcv-miR-rL1283p ) that can act on mammalian targets [215]

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Recent studies have highlighted the importance of the diet as a crucial factor influencing the onset and progression of RA [42, 43]

As a key energy substrate for tumor cells, Gln can be catabolized by glutaminase to generate -ketoglutarate (-KG), which directly enters the tricarboxylic acid (TCA) cycle [1]