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Mitochondrial quality control mechanisms, including mitophagy and fission/fusion dynamics, are essential at this stage to prevent chronic ROS leakage and restore redox homeostasis

In this context, there is an emphasis on the need for a deeper understanding of the functions of FOXO in the nervous system, which could lead to the development of targeted research approaches for these severe diseases

Zhang J, Wang S, Jiang B, Huang L, Ji Z, Li X, et al

List of studies Overview of EpitalonHighly Bioactive Pineal Tetrapeptide with Promising Properties Type of study: literature review Number of citations: 1 Year: 2025 Authors: Szymon Kamil Araj, Jakub Brzezik, Katarzyna Mdra-Gackowska, ukasz Szeleszczuk Journal: International Journal of Molecular Sciences Journal ranking: Q1 Key takeaways: Epitalon shows significant geroprotective and neuroendocrine effects, with potential mechanisms including antioxidant, neuro-protective, and antimutagenic effects

Crohns Colitis 17 (Suppl

According to qualitative and quantitative experimental data that were evaluated, GSH conjugation is the first upstream Key Event (KE) of this AOP, triggering oxidative stress (OS)