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L-carnitine may help support fat use without exercise, but is considered to be more effective when combined with physical activity

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For example, administration of the flavonoids rutin and quercetin has shown to diminish oxidative phenomena including lipid peroxidation, nitrosylation and iNOS expression, as well as pain symptomatology (thermal and mechanical allodynia) in treated mice compared to non-treated ones (Azevedo et al., 2013)

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