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Additional investigations are ongoing for: Non-alcoholic fatty liver disease (NAFLD/NASH) Sarcopenia (age-related muscle loss) Chronic kidney disease Ibutamoren exhibits greater potency and duration than earlier GH secretagogues and is under evaluation as a safer, more physiologic alternative to hGH therapy. Patel et al., The Journal of Clinical Endocrinology & Metabolism MK-677s ability to stimulate endogenous GH production without suppressing the bodys own hormone axis sets it apart from both injectable GH and peptide-based secretagogues like Sermorelin , Ipamorelin , or CJC-1295

This translates to approximately 1.6 to 4 mcg per kilogram of body weight, extrapolated from effective rat doses using standard interspecies scaling factors

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Strandberg E, Killian JA