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A number of diseases can exhibit similarities to MS, both relapsingremitting or primary progressive, often to the point of misdiagnosis even by specialists (Table 1)

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Muscle injury was induced in young (47 mo), old (20 mo) and geriatric (26 mo) C57BL/6J mice (Jackson Laboratory, 000664

When B12 levels drop, the resulting drop in SAMe leads to the hypomethylation of myelin basic protein