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The Journal of urology

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The images (Figure 6) showed that the nanocapsule did not penetrate the skin carrying the vitamin, but a deep permeation (around 30 m) of both was observed, which suggests that the drug present in deep skin layers was released from nanocapsules in the superficial skin layers

Alternatively or in concert with genetic testing, clinical and biochemical assessment should include a brief history relating to jaundice, liver disease, and subtle features of neurological or psychiatric involvement