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PBC was diagnosed according to international recommendations, response to Ursodeoxycholic acid (UDCA) was defined according to Paris-II criteria

Week 58: 4 mg once weekly

The pre-treatment with piperine before curcumin administration significantly increased curcumin oral bioavailability in all tested rats

Et Smith is native to East Asia and found in subtropical and tropical countries, including India, Taiwan, Brazil, Japan, and Malaysia (Kawai et al., 2021)

doi: 10.1016/j.freeradbiomed.2003.09.018 47

Additionally, the complex etiology of autism, involving the interaction of genetic and environmental factors, makes it easier to obtain accurate data by studying childhood biomarkers, minimizing interference from other factors