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Description

Generation of Knockout Plasmids and Transfections Two different plasmids (pL0001 and pL0034) were used to create a total of four knockout plasmids (Figure 1) to attempt disruption of the pbgst gene

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10.3389/fmed.2021.736978 189 StockwellB

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Indeed, it has been demonstrated a role of IGF-I signaling for maintaining glomerular integrity, restoring podocyte abnormalities, inhibiting podocyte apoptosis, and alterations in the glomerular basement membrane and the adjacent endothelial cell layer [140,363]

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