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Gallbladder: Increased risk of gallstones/cholelithiasis is documented with GLP-1 weight-loss dosing and is part of the class picture

In support, the counteracting effect of BPC 157 on L-NAME was parallel with its endothelium protection and mucosal integrity maintenance (33)

Whether cagrilintide or CagriSema preserves more lean mass than GLP-1 receptor agonists alone remains an open question that future studies need to address