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This raises the notion that perhaps within konzo-prone regions of sub-Saharan Africa there may be genetic variants of GPx3, or genes related to associated pathways that circulate which could alter gene expression and subsequently cause a reduction of protein abundances in these populations

Singapore: Springer

CZ: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Visualization, Writing original draft, Writing review & editing

Kacem, N.C., Destain, J., Meraihi, Z., Dehimat, L., Haddoum, T., Wathelet, J., et al., Afr

Upregulation in hepatic NQO1 gene expression was found in various rodent diet-induced or MSG-induced MASLD models (Deng et al

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