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Heyrovsk Institute of Physical Chemistry, Czech Academy of Sciences, Prague, Czech Republic, 3 J

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It is an important water-soluble antioxidant that plays a role in protecting the body from free radical oxidative stress, which can lead to premature aging of cells.It also acts in amino acid transport and detoxification pathways

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The salvage/recycling pathway Following NAD + biosynthesis via the de novo pathway, NAD + is degraded to NAM by various NAD + -consuming enzymes, including NAD + glycohydrolases, polyADP-ribose polymerases (PARPs), and sirtuins (SIRTs)